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Thursday, September 3, 2020
Antimicrobial Activity of Pyrimidine-5-carboxylic Acid
Antimicrobial Activity of Pyrimidine-5-carboxylic Acid Antimicrobial movement of blended, novel hydroxamic corrosive of pyrimidine-5-carboxylic corrosive and its edifices with Cu(II), Ni(II), Co(II) and Zn(II) metal particles Bhawani Shankar, Rashmi Tomar, Madhu Godhara, Vijay Kumar Sharma Unique Four metal edifices of new hydroxamic corrosive, 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) with Cu(II), Ni(II), Co(II) and Zn(II) metal particles have been combined. The hydroxamic corrosive and its metal buildings were portrayed by basic diagnostic procedures, for example, continued liquefying point (M.P.) assurance, natural investigation, running their flimsy layer chromatography for single spot, and spectroscopic methods, for example, I.R., H1-NMR and UV-Vis. (just for metal chelates) spectroscopy. Antimicrobial movement of the hydroxamic corrosive and their metal buildings were screened against two types of microscopic organisms and two types of parasites by Serial Dilution Method. Metal edifices were discovered progressively dynamic against the two microorganisms just as parasites in antimicrobial screening test. Watchwords Hydroxamic acids, antimicrobial movement, metal buildings Presentation Hydroxamic acids show a wide range of natural exercises and for the most part have low poison levels à ¯Ã¢ â⬠º1㠯â â -à ¯Ã¢ â⬠º2㠯â â . Hydroxamic acids are very notable for their antibacterial à ¯Ã¢ â⬠º3㠯â â -à ¯Ã¢ â⬠º5㠯â â , antifungal à ¯Ã¢ â⬠º6㠯â â -à ¯Ã¢ â⬠º7㠯â â , antitumor à ¯Ã¢ â⬠º8㠯â â -à ¯Ã¢ â⬠º9㠯â â , anticancer à ¯Ã¢ â⬠º10㠯â â , antituberculosis à ¯Ã¢ â⬠º11㠯â â and antimalerial à ¯Ã¢ â⬠º12㠯â â properties. Hydroxamic acids are inhibitors of proteins, for example, prostaglandin H2 synthatase à ¯Ã¢ â⬠º13㠯â â , peroxidase à ¯Ã¢ â⬠º14㠯â â , urease à ¯Ã¢ â⬠º15㠯â â and framework metalloproteinase à ¯Ã¢ â⬠º16㠯â â . Cinnamohydroxamic acids are utilized for treatment of the indications of asthma and other obstructive aviation route maladies which repress 5-lipoxygenase à ¯Ã¢ â⬠º17㠯â â . Various hydroxamic corrosive analogs have been appeared to restrain DNA (dinucleic corrosive) amalgamation by inactivating the catalyst ribonucleotide reductase (RNR) à ¯Ã¢ â⬠º18㠯â â . Normally occurringhydroxamic corrosive, 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) is a powerfulantibiotic present inmaize à ¯Ã¢ â⬠º19㠯â â . Antiradical and cancer prevention agent properties of hydroxamic acids have additionally been watched à ¯Ã¢ â⬠º20㠯â â . Hydroxamic acids assume significant job in numerous synthetic, biochemical, pharmaceutical, investigative, and modern fields à ¯Ã¢ â⬠º21㠯â â -à ¯Ã¢ â⬠º25㠯â â . These different natural exercises of hydroxamic acids are because of their complexing properties towards progress metal particles à ¯Ã¢ â⬠º26㠯â â -à ¯Ã¢ â⬠º27㠯â â . Siderophores are Fe(III) buildings of normally happening hydroxamic acids, associated with the procedures of iron vehicle from nature to the living life forms à ¯Ã¢ â⬠º28㠯â â -à ¯Ã¢ â⬠º29㠯â â . Hydroxamic acids after deprotonation goes about as bidentate ligands and octahedral buildings are framed through the co-appointment of two oxygen molecule of the ââ¬CONHO-gathering. This kind of co-appointment have been concentrated with Cr(III), Fe(III), Ni(II), Co(II) and Zn(II) particles in strong state just as in arrangements, showing the development of octahedral buildings à ¯Ã¢ â⬠º30㠯â â . We report thus the blend, basic highlights and antimicrobial action of new hydroxamic corrosive, 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) just as their metal edifices 4a-d with Cu(II), Ni(II), Co(II) and Zn(II) metal salts. Test Reagents and techniques All synthetic utilized in the current examination were of scientific reagent grade. 1,3-Di-p-tolylbarbituric corrosive was incorporated by recently known strategy in the research center. Copper acetic acid derivation monohydrate, nickle acetic acid derivation tetrahydrate, cobalt acetic acid derivation tetrahydrate and zinc acetic acid derivation dihydrate were bought from E-Merck. Triethyl amine and ethyl chloroformate were bought from Spectrochem. Hydroxylamine hydrochloride potassium hydroxide and diethyl ether were gotten from S.D. fine synthetic compounds restricted, India. All the integrated mixes were broke down for C, H and N by basic analyser, model 1108 (EL-III). H1-NMR spectra (400MHz) were recorded on JNM ECX-400P (Jeol, USA) spectrometer utilizing TMS as an inside norm. IR retention spectra were recorded in the 400-4000 cm-1 territory on a Perkin-Elmer FT-IR spectrometer model 2000 utilizing KBr beds. UV-Vis. spectra of metal buildings were recorded in DMSO dissolvable a t room temperature on Simadzu Spectro Photometer model no. 1601. Dissolving focuses were resolved utilizing Buchi M-560 and are uncorrected. These responses were checked by dainty layer chromatography (TLC), on aluminum plates covered with silica gel 60 F254 (Merck). UV radiation and iodine were utilized as the imagining specialists. Blend of the hydroxamic corrosive 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) Blend of ligand 3 was completed in two stages as follows: Stage 1: Synthesis of ethyl 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylate (2). Ethyl 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylate (2) was integrated by the revealed strategy for Kuhne et al à ¯Ã¢ â⬠º31㠯â â . 1,3-Di-p-tolylbarbituric corrosive à ¯Ã¢ â⬠º5g, 0.016 mol.㠯â â and triethyl amine à ¯Ã¢ â⬠º2.30ml, 0.0168 mol.㠯â â and dimethyl aminopyridine (DMAP) à ¯Ã¢ â⬠º0.10g㠯â â were broken up in 20 ml of dichloromethane (DCM) and the arrangement was cooled to 00 C. At that point ethyl chloroformate à ¯Ã¢ â⬠º1.60ml, 0.0165 mol.㠯â â was included drop-wise over 30 minutes. The blend was in this way mixed for 12 hours at 00C, at that point, permitted to warm to the room temperature for 7 hours. The item is removed in chloroform and dried over Na2SO4. Further, chloroform was dissipated to dryness and unrefined item was recrystallised from ethyl liquor to yield unadulterated 2. Stage 2: 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) from ethyl 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylate (2). Combination of 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) was completed by embracing a technique like that portrayed by Griffith et al à ¯Ã¢ â⬠º32㠯â â . The blend of hydroxylamine hydrochloride à ¯Ã¢ â⬠º1.87g, 0.026 mol. à ¯Ã¢ â and watery potassium hydroxide à ¯Ã¢ â⬠º2.19g, 0.039 mol. à ¯Ã¢ â was added drop-wise to a methanolic arrangement of ethyl 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylate (2) à ¯Ã¢ â⬠º5g, 0.013 mol. à ¯Ã¢ â . The arrangement was blended at room temperature for 72 hours and afterward fermented to pH 5.5 utilizing 5% HCl arrangement. After filtration the dissolvable was evacuated in vacuo to yield a strong. The unrefined item was recrystallised from heated water to yield unadulterated compound 3. Combination of metal buildings Combination of Cu(II), Ni(II), Co(II) and Zn(II) buildings of 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3). Copper acetic acid derivation monohydrate à ¯Ã¢ â⬠º0.136g, 0.00068 mol.㠯â â in chilly water was added with mixing to 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) à ¯Ã¢ â⬠º0.50 g, 0.00136 mol.㠯â â in EtOH (20 ml) in a round base cup. The substance were blended for around 6 hours and afterward decrease to half volume under vacuo. Yellowish earthy colored encourage of 4a was showed up subsequent to including oil ether. The hasten was separated, washed with limited quantities of Et2O and dried over CaCl2 in a vacuum desiccator. Thus, edifices 4b of Ni(II) , 4c of Co(II) and 4d of Zn(II) with 2,4,6-trioxo-1,3-di-p-tolyl-1,2,3,4,5,6-hexahydropyrimidine-5-carboxylic corrosive hydroxamide (3) were incorporated by taking nickle acetic acid derivation tetrahydrate, cobalt acetic acid derivation tetrahydrate and zinc acetic acid derivation dihydrate separately. Infrared Spectra In the IR spectra (Table 1), carbonyl extending vibrations of hydoxamic corrosive display a medium sharp force band in the locale 1660 cm-1 à ¯Ã¢ â⬠º33㠯â â . This band has moved towards negative locale 1626-1609 cm-1 in the metal edifices demonstrating the coordination of the ligand with the metal particle through oxygen of the carbonyl gathering. The symmetric N-O extending vibrations, got in the district 1120 cm-1 in the IR spectra of ligands, have moved to bring down side in the IR spectra of their metal edifices recommending the coordination of ligand to the metal particle through oxygen of the N-O moiety à ¯Ã¢ â⬠º34㠯â â . The nearness of water particles inside coordination circle of all chelates were bolstered by expansive groups in the area 3450-3280 cm-1 and 850-800 cm-1 because of extending and twisting methods of facilitated water atoms, individually. The presence of new band in the IR spectra of metal chelates in the area 551-519 cm-1 is plausible because of development of M-O bonds à ¯Ã¢ â⬠º35㠯â â . Table 1. IR ghastly information of hydroxamic corrosive 3 and its metal buildings 4a-d. Compound à ¯Ã à ®(C=O)cm-1 à ¯Ã à ®(C-N) cm-1 à ¯Ã à ®(N-O) cm-1 à ¯Ã à ®(M-O) cm-1 3 1660 1349 1120 4a 1609 1327 1036 551 4b 1624 1355 1023 519 4c 1626 1384 1023 540 4d 1629 1350 1025 541 H1-NMR Spectra The hydroxamic corrosive 3 shows a one proton singlet at 1.14 due to ââ¬NH-O proton, most likely because of attractive aniso
Tuesday, August 25, 2020
The Rosenbaum House :: essays papers
The Rosenbaum House The 1920ââ¬â¢s and the 1930ââ¬â¢s were critical occasions in engineering society. During this time, in addition to the fact that architecture was evolving, society. The car was getting famous among family units, urban communities were blasting, and urbanization was in full impact. This was a key time for progression in the engineering scene. Right now, presently renowned modelers, for example, Frank Lloyd Wright, Mies van der Rohe, Walter Gropius and Le Corbusier began what is currently known as the Modernist Movement. Today this Modernist Movement and these engineers have molded what we look like at and characterize design. Of these modelers, Frank Lloyd Wright is among a portion of my top picks. In 1939, Wright structured a house known as the Rosenbaum house, which at the time was totally against what engineering was. Yet, albeit distinctive to the standard, this house was reforming what design would be. I loved Wrightââ¬â¢s structures and design better than the others on account of numerous perspectives. Wright erased the storage rooms and cellars out of his homes, the living zones were progressively extensive and open, and the outside is truly brought into the inside. His thoughts are increasingly utilitarian for my specific way of life, and the monks are substantially more satisfying than the wants of different houses. While Le Corbusier was attempting to handle the issues of lodging expenses and attempting to make a plan for large scale manufacturing, he forgot about the uniqueness and the religious zealots of what Wright has achieved. I didn't care for the case like model of Corbusierââ¬â¢s plan since it holds no specific style to some different houses he had structured. Another part of Corbusierââ¬â¢s configuration was that his structures were made basically for large scale manufacturing and inexpense, yet they are not redone to the individual needs and wants of its oc cupants, which I don't have confidence in. I don't care for van der Roheââ¬â¢s house in light of the fact that the ideas he fused were intended for business use, for example, workplaces in his tall building structures. His toning it down would be best idea is an exceptionally solid design thought that is still extremely noticeable today, yet I don't care for my homes to show its system and be totally open to its environmental factors. I don't accept van der Rohe joins open and private spaces in his structures. Wrightââ¬â¢s thoughts were ideal for the general public at the hour of structure.
Saturday, August 22, 2020
Hiroshima and Nagasaki Day Free Essays
Hiroshima Peace Day falls on August 6 and Nagasaki Peace Day on August 9. The two days to help the world to remember the decimation that a war can wreck. As indicated by gauges the bombs slaughtered an enormous number of individuals â⬠with most of the causalities having kicked the bucket from blaze or fire consumes. We will compose a custom article test on Hiroshima and Nagasaki Day or then again any comparable subject just for you Request Now What was the deal? In 1945, the United States of America dropped two nuclear bombs on the urban communities of Hiroshima and Nagasaki in Japan. On August 6, the atomic weapon ââ¬Å"Little Boyâ⬠was dropped on Hiroshima since it was a city of extensive military significance and contained Japanââ¬â¢s Second Army Headquarters. It additionally was the correspondences community and capacity terminal. On August 9, at 11:02 a. m. , at a height of 1,650 feet, Fat Man (right) detonated over Nagasaki. The yield of the blast was later assessed at 21 kilotons, 40 percent more prominent than that of the Hiroshima bomb. Inside the initial two to four months of the bombings, the intense impacts killed 90,000 â⬠166,000 individuals in Hiroshima and 60,000 â⬠80,000 in Nagasaki, with generally 50% of the passings in every city happening on the primary day. Six days after the explosion over Nagasaki, on August 15, Japan reported its acquiescence to the Allied Powers, marking the Instrument of Surrender on September 2, formally finishing the Pacific War and along these lines World War II. Germany had marked its Instrument of Surrender on May 7, finishing the war in Europe. The bombings drove, to some degree, to post-war Japan receiving Three Non-Nuclear Principles, denying the country from atomic deadly implement. Instructions to refer to Hiroshima and Nagasaki Day, Essay models
Friday, August 21, 2020
Krakauerââ¬â¢s life Essay
In April of 1992 a youngster named Chris McCandless, from a prosperous and adoring family, caught a ride the nation over to Alaska. He gave $25,000 of his reserve funds to good cause, left his vehicle and about the entirety of his assets. He consumed all the money he had in his wallet, and made another life. After four months, his body was found in a surrendered transport. Jon Krakauer developed a journalistic record of McCandlessââ¬â¢s story. Verging on fixation, Krakauer searches for the pieces of information to the secret that is Chris McCandless. What he finds is the exceptional draw of the wild on our creative mind, the intrigue of high-chance exercises to youngsters. When McCandlessââ¬â¢s botches end up being deadly he is excused for his naivetã ©. He was said by some to have a desire to die, yet needing to bite the dust and needing to perceive what one is equipped for are too altogether different things. I started to inquire as to whether Chris truly wasnââ¬â¢t as insane as certain individuals suspected. At that point I understood it was very conceivable that individuals thought he because insane was on the grounds that he had kicked the bucket attempting to satisfy his fantasy. In the event that he had left his experience like Krakauer, individuals would have lauded him instead of criticism. So I posed the inquiry, ââ¬Å"How does Krakauerââ¬â¢s life equal Chris McCandlesses?â⬠Chris and Jonââ¬â¢s life have numerous equals and complexities simultaneously. Both surrendered a large portion of their assets to pursue a fantasy they had. Ones dream was to live off the land in the remote areas of Alaska, the other also climb the Devils Thumb, a mountain top that had never been scaled by man. Each man knew about the dangers, yet would they say they were similarly arranged when each started their own experience? I feel that Chris McCandless was off guard when he originally began. Raised by a well off family and simply moving on from Emory University I feel he wasnââ¬â¢t as readied as he could have been. Luckily his dad had taken him on climbing trips so he was in any event to some degree acquainted with the wild however not the slightest bit was he arranged at all for the seriousness of the Alaskan wild. I figure it would have been a significant accomplishment only for Chris to have had the option to live off the land in a neighborhood timberland. To be reasonable for Chris Iââ¬â¢m sure Krakauer didnââ¬â¢t start off by only one day concluding he would climb the Devils Thumb after he was roused by making it up the climbing divider at the nearby province reasonable. The two men needed to progressively stir their way up to achieving their objectives. Jon did this byâ many other littler ascensions and Chris stirred his way up by contemplating nature books and wandering over the U.S. So along these lines Jon and Chris were indistinguishable despite the fact that their objectives were unique. Another way the two were comparable was the way that the two of them had family issues. In spite of the fact that his folks and sister cherished him Chris subtly disdained his folks for concealing the way that his dad had been raising two separate families. Much the same as Chrisââ¬â¢s father Lewis Krakauer had just started to set him up for a vocation that he didnââ¬â¢t need to be any piece of. I think the two children were devoured by a kind of visually impaired fury when they discovered that their dads were not exactly great. This annoyance filled them to revolt and conflict with their dads wishes to make their own prospects. The greatest (and generally self-evident) distinction among Jon and Chris is that one kicked the bucket experienced his fantasy and the other lived to leave it. A great many people would state that Chris fizzled in light of the fact that his objective was to get by in the wild. Others would state that Jon succeeded on the grounds that he made it too the top and lived to tell his story. Anyway were the episodes actually that extraordinary? Chris lived in the Alaskan wild very nearly a hundred days before his portentous slip-up that cost him his life. Jon additionally had a couple of game changing errors that could have cost him his life however didnââ¬â¢t, similar to the time he got his tent ablaze or when his gracefully plane couldnââ¬â¢t come in light of awful climate. A great many people wouldnââ¬â¢t even fantasy about doing both of these accomplishments. At the point when the dangers are as high as both of these men confronted, even the most straightforward of missteps can demonstrate lethal. I imagine that on the off chance that Chris was viewed as a disappointment, at that point so ought to Jon. I think this in light of the fact that Jonââ¬â¢s unique objective was to climb the unclimbed area of The Devils Thumb. When Jon couldn't achieve this he backtracked and found a simpler, as of now climbed way. Anyway I feel that the two men were effective in their own specific manners. Chris made due for an all-encompassing timeframe without the assistance of human progress yet because of the toxic potato seeds he ate he was too powerless to even consider hiking back to development. Jon understood his constraints and realized he had to bring down his objective or face passing. On the off chance that anybody was a disappointment it was Jon in light of the fact that he called it quits from his underlying objective. Since the time I was a little kid I have been an outdoorsman. I love to go outdoors and go on climbs. At day camp I would climb the stone heaps and go investigating. I can identify with both Jon and Chrisââ¬â¢s requirement for experience. Indeed, even here at school I keep on adoring the outside. I utilize the climbing tower at the ARC, go snowboarding on the sledding slope, and go running on ROTC trails (during warm climate). Be that as it may, despite the fact that I love the outside I still donââ¬â¢t have the stuff to do what both of these men attempted to do. I know my restrictions and wouldnââ¬â¢t need to chance my life stupidly. I know its conceivable that I could figure out how to yet lamentably for my entire life I have been instructed that some time or another Iââ¬â¢ll set off for college, find a decent line of work, get hitched, have children and carry on with an upbeat, uneventful life. Which is the reason I respect Jon and Chris, both had the fearlessness to conflict with the standard of society and simply go do what they felt like. Donââ¬â¢t misunderstand me I love my life however a few days I wish I could do what they did, simply discard every one of my assets and stresses and simply do what I truly need to do. Bounce Marshal put it best when he said ââ¬Å"For me, and for thousands with comparative tendencies, the most significant energy of life is the overwhelming want to escape intermittently from the grip of an unthinking human progress. To us the satisfaction in isolation, complete freedom, and the magnificence of unsullied displays is significant to happinessâ⬠(Outdoorclub). Since the time man started to investigate we want to overcome and know the obscure. In the times of the Wild West youngsters would move their families westbound looking for experience and opportunity ââ¬Å"the wild ones, the men of the wild frontierâ⬠(Wayne 1). This drive, this show fate, ââ¬Å"the incredible weight of individuals moving consistently to new outskirts, looking for new grounds, new force, the full opportunity of a virgin world, has managed our course and framed our polices lake a Fate,â⬠(Weinberg 1) is the thing that constrained Jon and Chris to contradict some common norms of society and follow their fantasies. With less and less ââ¬Å"New Frontiersâ⬠these two had to depend on one of the last unconquered areas of the world, Alaska. It was there that they confronted their feelings of dread and defeated hardships to succeed. Taking everything into account I believe that one reason Krakauer chose to expound on Chris McCandless is the way that he found such huge numbers of upsetting coincidencesâ about his own life that he felt committed to reveal to Chrisââ¬â¢s story. I think it is very conceivable Jon feels regretful about having endure when Chris kicked the bucket. In any case, I think the two men were achievement full despite the fact that the two of them had totally different objectives and results. Works Cited Outdoorclub. 01 Mar. 2005 . Wayne, Bennett. Men of the Wild Frontier. Champaign: Garrard Publishing Organization, 1968. Weinberg, Albert. show Destiny. Baltimore: Johns Hopkins Press, 1935.
Tuesday, August 4, 2020
Doing research 277 feet off the ground
Doing research 277 feet off the ground Last week, I was lucky enough to get to see something very unique: the view from on top of Cambridges tallest building. The MIT Radio Society is raising awareness about the upcoming Green Building renovations, and they took me on a tour so that I could tell you about all the super-cool things theyre doing up there. Source: https://commons.wikimedia.org/wiki/Fi le:Green_Building,_MIT,_Cambridge,_M assachusetts.JPG You probably recognize the Green Buildings weird silhouette, but maybe, like me, hadnt thought about why it looks that way. The Radio Society taught me about the various antennae and took me inside the two radomes (yes, that giant sphere is a thing you can stand inside !!!). We also spent a good deal of time taking in the view of Boston and Cambridge from 21 floors up (we had to take TWO elevators). The radomes (short for radar dome) are actually just fibreglass shells, built to keep out the wind and rain but be permeable to radio waves. They protect two big satellite dishes, which are used to communicate with people around the world as well as for radio astronomy. With the power turned off, these radomes are safe to enter to do maintenance or just look around. (All the beautiful photos in the rest of this blog post are by Leif C. 23.) The fibreglass itself is in good condition, but the paint on top of it is old and peeling, which creates this beautiful mottled flamey look. On the roof itself, its often very windy, and that day it was about -8 degrees C. But inside the dome (once youve hauled yourself up the extremely cold metal ladder, anyway), its quiet and much warmer. Although much of the electrical equipment is very recent, the dishes themselves are older, and you can tell: they have history written right on them! Take a look at those dates, baby. We spent some time in the domes, as well as inside the shack (the headquarters of the society), while I learned about all the projects going on on the roof. Here are just a few: -A physics undergraduate recently used the big radome dish to map out the rotation of our galaxy by finding the Doppler shift in the frequencies of hydrogen emission spectra at various points, and using that to calculate the velocity of the matter (star, etc.) at those points. -EME, or Earth-Moon-Earth communication. Bouncing radio signals off of the moon, rather than aiming them directly at the earth, allows the radio operator to talk to anyone anywhere on the planet. Past Radio Society connections have included Texas, California, Europe, and Australia. Recently, they communicated with the Arecibo Observatory in Puerto Rico after the earthquakes in the beginning of January, and received the news that the Observatory was a bit shaken up, but safe from the worst of the damage. (A system like this could be very useful in the case of a large-scale natural disaster in the US, when more commonly-used lines of communications like telephones might be out of service.) -An APRS (automated packet reporting system) antenna. The APRS antenna works as a repeater: it collects packets of data being emitted nearby, like GPS signals from a computer, information from a weather station, or a packet from another repeater, and sends them out to further repeaters to help them reach their destination. For a long time, the Radio Society didnt think that their APRS antenna was doing much and then it went down, and they found out just how useful it was to everyone else. Today, they have a system set up to raise an alert after even just a few minutes of downtime, and the antenna handles thousands of packets per day, helping everyone in the Cambridge area get their data where it needs to be. -An ADS-B (Automatic dependent surveillance â" broadcast) receiver. ADS-B is the system that airplanes use to broadcast their position automatically. These broadcasts are very useful to other planes and to air traffic controllers, of course, but anyone else with a receiver can also pick them up. In the future, the Radio Society is hoping to develop a couple really interesting projects based around ADS-B. One is actually a machine learning program: can a computer be taught to predict the future location of an airplane based on past data? The other involves bouncing other radio signals off the airplane. This would require being able to accurately calculate the planes future location, but could greatly increase the range of the radio waves. There are even more projects planned for the future, but things have been moving more slowly lately as club efforts focus on the renovations. The roof continues to be in use, though, as other groups, labs, and classes use it for research and learning. The Societys ultimate dream would be to use these renovations as a chance to increase these other uses even more. The Green Buildings roof is one of the only rooftop radio/signal lab spaces on campus open to students and it is the only handicap accessible rooftop lab space at MIT. It could be a fantastic space, open to all parts of the MIT community, where research of all types is done. Of course, I went on this tour with the express purpose of writing about it on the blogs. But beyond the research being done here (which is very, very cool), I was struck by just how much this lab space, and the Radio Society, embody some of what is so special about MIT. We are a place where students teach other students; where you can learn skills you cant learn anywhere else; where anyone is happy to teach you anything, if you only show up and ask. Engineering for social good and learning by doing have become buzzwords of late, but here at MIT they have always been in the water, powering so much of what we do. The Radio Society is currently fundraising to support the continued existence of their antennae, the two radomes, and their shack headquarters. They are already partway to their goal of $300,000 to retain the shack. Unfortunately, administration has set much higher fundraising targets in order to keep the elevator to the roof (so that everyone can see the view I saw yesterday, no matter their level of mobility) and the equipment (needed for all these amazing research projects); the Society is still in talks with them to set the exact amount. If youd like to make a donation to help them preserve this space, or want to get involved with their campaign, information on how to do so is available at their website: http://w1mx.mit.edu. And thanks for listening :) Post Tagged #Green Building #MIT Radio Society
Monday, June 22, 2020
Transmedia Storytelling and Advertising Watching a Video - 550 Words
Transmedia Storytelling and Advertising: Watching a Video (Essay Sample) Content: Name Instructor Course DateTransmedia Storytelling and AdvertisingQuestion 1Transmedia storytelling is a timely concept. The emergence of different media platforms and variety in consumer preferences cuts across even in the field of entertainment. The fact, therefore, calls for diversity in service provision to keep up with the evolutions. The move to transmedia story telling ensures that every individual gets the same entertainment opportunity in tandem with their characteristics. The values and ideologies set to be transmitted by a particular production have the possibility of reaching different kinds of individuals in different ways. The adoption of this multi layered approach ensures the messages being conveyed are relevant to everyone. The current generation, for example rely so much on electronic media and are more attracted to visuals and musicals. They pay less attention to hardcover materials and as such books may not be ideal. In contrast, the older generati on is less conversant with the advancing technology and thus the hardcover materials may be appropriate for them. Advantageous is the fact that the multilayered approach enhances the understanding. A concept missed while reading a book can be captured while watching it in a movie. The multilayered approach can be made better if the suggested corrections are considered. More emphasis should be put on collaboration to ensure rather than competition for monetary gain. Advancement into different market segments with integration of new characters or concepts to ensure sustained costumer interest and loyalty can make the approach better.Question 2The suggested trends and changes are likely to inspire innovation in the field of advertised planning. The increased popularity in this approach leads to future expectation by the consumers for the full adoption of this mode of advertisement. Emergence of new business models in the advertisement industry is expected, but majorly those that focus on the relationship between the company and consumer unlike the previous ones that focused on company to company. Gene rally, there is foreseeable improvement in quality and content.Question 3Transmedia approach has been incorporated in current advertising practices largely. The quality and success in communicating the intended message differs from one company to another. Let us consider an example of Coca-Cola Company. They use several platforms rolled up into on...
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